Evidence Synthesis on Gait and Balance Training: Meta-Analysis of Physical Therapy Intervention in Parkinson’s Patients

Physical Therapy in Parkinson Disease


  • Paras Ayaz Indus University
  • Qasim Raza Indus Hospital and Heath Network Karachi
  • Misbah Anis Tabba Liaquat National Hospital and Medical College
  • Muhammad Umer Baig Ziauddin University


Gait, Parkinson Disease, Postural Balance, Risk of Fall


Background: Parkinson Disease is considered to be posing a significant impact worldwide. According to the Global Burden of Disease study (GBD), there has been 1.02 million incident cases recorded in 2017 and 6.1 million cases worldwide in 2016. Between 1990 and 2016, the standardized rate of age among Parkinson's disease prevalence rose by 21.7%.

Methods: Studies examining the effects of physiotherapy on balance, gait and other pertinent outcomes among individuals with PD undergoing rehabilitation program were included in the inclusion criteria. Studies performed between 2015 and 2023 were taken into account for inclusion.  Studies conducted in languages other than English, or those that did not have readily available open access or for which open access could not receive after contacting corresponding authors were all excluded.

Results: The risk of bias assessment was performed based on the guidelines of SYRCLE. The author- The findings of this meta-analysis examining the effectiveness of rehabilitation on balance across different trials. Results of fixed-effects model analysis indicated that physical therapy showed a statistically significant favorable influence on balance among individuals with Parkinson's disease, with an overall affect size (Standardized Mean Difference, SMD) of 0.511 (95% CI: 0.255 to 0.766). A somewhat greater impact size of 0.654 (95% CI: 0.0441 to 1.264) was seen in the model of the random-effects. Noticeable heterogeneity was detected in the test (Q = 32.8633, DF = 6, p < 0.0001), indicating a highest degree of variability among included studies.

Conclusion: In conclusion, a thorough meta-analysis of research on the influence of physical therapy treatments on gait, balance among people with Parkinson's disease found positive findings.

Author Biographies

Paras Ayaz, Indus University

Lecturer, Department of Physical Therapy

Qasim Raza, Indus Hospital and Heath Network Karachi

Senior Physiotherapist, Department of Physiotherapy

Misbah Anis Tabba, Liaquat National Hospital and Medical College

Senior Physiotherapist, Department of Physiotherapy

Muhammad Umer Baig, Ziauddin University

Lecturer, College of Physical Therapy, faculty of Allied Health Sciences


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Systematic Review and Meta-Analyses