Frequency of Gall Stones in Patients with Acute Pancreatitis at Tertiary Care Hospital of Karachi, Pakistan
Frequency of Gall Stones in Acute Pancreatitis
Keywords:
Abdomen, Acute Pancreatitis, Gallstones, PrevalenceAbstract
Background: In developed countries, the adult population has a 20% incidence of gallstones, with a rise of 0.60 to 1.39% yearly. Our study aimed to determine the frequency of gallstones in Acute Pancreatitis (AP) patients.
Methods: A cross-sectional study was conducted at Abbasi Shaheed Hospital, Karachi, recruited all patients fulfilling inclusion criteria presented in the general surgery department from 3rd Oct 2020 to 3rd Oct 2021. After ethical approval and consent, a brief history was taken, and clinical examination, laboratory investigations, and ultrasound of the upper abdomen were done to ascertain the frequency of gallstones.
Results: A total of 93 patients diagnosed with AP were included in this study. Of these, 70 (50.6%) were male patients, and 23 (49.4%) were females, with a mean age of 40.752+11.764 years. The gallstones were found in 42 (45.2%) patients.
Conclusion: The frequency of gallbladder stones was high in patients with AP. A prompt or a late diagnosis can directly affect a patient’s mortality and morbidity.
References
Li J, Chen J, Tang W. The consensus of integrative diagnosis and treatment of acute pancreatitis‐2017. Journal of Evidence‐Based Medicine. 2019 Feb;12(1):76-88.
Pagliari D, SAVIANO A, Mancarella FA, LAGO AD, Serricchio ML, GASBARRINI A, BRIZI M, Manfredi R, NEWTON E, ATTILI F. Clinical assessment and management of severe acute pancreatitis: a multi-disciplinary approach in the XXI century. European Review for Medical & Pharmacological Sciences. 2019 Jan 15;23(2).
Anukethan J. Timing of Cholecystectomy for Biliary Pancreatitis (Doctoral dissertation, Rajiv Gandhi University of Health Sciences (India)).
Trust MD, Sheffield KM, Boyd CA, Benarroch-Gampel J, Zhang D, Townsend Jr CM, Riall TS. Gallstone pancreatitis in older patients: are we operating enough?. Surgery. 2011 Sep 1;150(3):515-25.
Sarvani C, Sireesh D, Ramkumar KM. Unraveling the role of ER stress inhibitors in the context of metabolic diseases. Pharmacological research. 2017 May 1;119:412-21.
Lee PJ, Papachristou GI. Management of severe acute pancreatitis. Current treatment options in gastroenterology. 2020 Dec;18:670-81.
Bálint ER, Fűr G, Kiss L, Németh DI, Soós A, Hegyi P, Szakács Z, Tinusz B, Varjú P, Vincze Á, Erőss B. Assessment of the course of acute pancreatitis in the light of aetiology: a systematic review and meta-analysis. Scientific Reports. 2020 Oct 21;10(1):17936.
Pu W, Luo G, Chen T, Jing L, Hu Q, Li X, Xia H, Deng M, Lü M, Chen X. A 5-year retrospective cohort study: epidemiology, etiology, severity, and outcomes of acute pancreatitis. Pancreas. 2020 Oct 1;49(9):1161-7.
Del Vecchio Blanco G, Gesuale C, Varanese M, Monteleone G, Paoluzi OA. Idiopathic acute pancreatitis: a review on etiology and diagnostic work-up. Clinical journal of gastroenterology. 2019 Dec;12(6):511-24.
Walkowska J, Zielinska N, Karauda P, Tubbs RS, Kurtys K, Olewnik Ł. The pancreas and known factors of acute pancreatitis. Journal of Clinical Medicine. 2022 Sep 22;11(19):5565.
Gurusamy KS, Nagendran M, Davidson BR. Early versus delayed laparoscopic cholecystectomy for acute gallstone pancreatitis. Cochrane Database of Systematic Reviews. 2013(9).
Jee SL, Jarmin R, Lim KF, Raman K. Outcomes of early versus delayed cholecystectomy in patients with mild to moderate acute biliary pancreatitis: a randomized prospective study. Asian journal of surgery. 2018 Jan 1;41(1):47-54.
Bertilsson S, Swärd P, Kalaitzakis E. Factors that affect disease progression after first attack of acute pancreatitis. Clinical Gastroenterology and Hepatology. 2015 Sep 1;13(9):1662-9.
KARCIOGLU O, YENİOCAK S, HOSSEINZADEH M, SEZGIN SB. Abdominal Pain: Essential Diagnosis and Management in Acute Medicine. Bentham Science Publishers; 2022 Aug 31.
Portincasa P, Molina-Molina E, Garruti G, Wang DQ. Critical care aspects of gallstone disease. The Journal of Critical Care Medicine. 2019 Jan 1;5(1):6-18.
Portincasa P, Di Ciaula A, de Bari O, Garruti G, Palmieri VO, Wang DH. Management of gallstones and its related complications. Expert review of gastroenterology & hepatology. 2016 Jan 2;10(1):93-112.
Shabanzadeh DM. New determinants for gallstone disease. Dan Med J. 2018 Feb 1;65(2):B5438.
Downloads
Published
Issue
Section
License
Copyright (c) 2024 Dr Fatima Iqbal, Dr. Sobia Majeed, Dr Omama Subul Islam, Dr Imran Ahmed Khan, Dr Muhammad Jamal ud Din, Dr Muhammad Khurram Zia
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
